Trial intelligence / Profile preview

DESTINY-Lung06 first-line HER2-overexpressing non-squamous NSCLC trial

2024-515658-26-00Phase 3Authorised

Sponsor
Daiichi Sankyo Co., Ltd.
Start
Jan 2026
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
24
01

Overview

Phase 3, randomised, open-label trial of trastuzumab deruxtecan, pembrolizumab, carboplatin, cisplatin and pemetrexed in Non-small cell lung cancer (NS-NSCLC) and non-small cell lung cancer (NSCLC) (2 arms), sponsored by Daiichi Sankyo Co., Ltd. Primary endpoint: Progression-free survival. Planned start Jan 2026; status: authorised.

02

Drugs

trastuzumab deruxtecanpembrolizumabcarboplatincisplatinpemetrexed
03

Conditions

Non-small cell lung cancer (NS-NSCLC)non-small cell lung cancer (NSCLC)

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