Trial intelligence / Profile preview

HAELO phase 3 study of NTLA-2002 in hereditary angioedema

2024-515741-42-00Phase 3Authorised

Sponsor
Intellia Therapeutics
Start
Mar 2025
Modality
CRISPR-Cas9 → CRISPR Systems → Programmable Nucleases → Gene Editing → Gene Therapies, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
9
01

Overview

Phase 3, randomised, double-blind trial in hereditary angioedema (HAE) comparing NTLA-2002 with Placebo (2 arms). Primary endpoint: Time-normalized number of Investigator-confirmed HAE attacks from Week 5 through Week 28. Planned start Mar 2025; status: authorised.

02

Drugs

lonvoguran
03

Conditions

hereditary angioedema (HAE)

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