Trial intelligence / Profile preview

KEYMAKER-U01 Substudy 01G in treatment-naïve stage IV non-small cell lung cancer

2024-515772-12-00Phase 2Authorised

Sponsor
Merck & Co.
Start
Apr 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
11
01

Overview

Phase 2, randomised, open-label trial of pembrolizumab and patritumab deruxtecan in non-small cell lung cancer (NSCLC) (4 arms), sponsored by Merck & Co. Primary endpoints: Objective Response Rate, Number of participants with adverse events and 1 more. Planned start Apr 2025; status: authorised.

02

Drugs

pembrolizumabpatritumab deruxtecan
03

Conditions

non-small cell lung cancer (NSCLC)

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