Trial intelligence / Profile preview

POCHI: pembrolizumab with XELOX or FOLFOX-bevacizumab in MSS metastatic colorectal cancer with high immune infiltrate

2024-515788-73-00Phase 2Authorised

Sponsor
Fédération Francophone de Cancérologie Digestive
Start
Jul 2024
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label trial of pembrolizumab, bevacizumab, oxaliplatin, capecitabine and fluorouracil in colorectal cancer (CRC) and colorectal adenocarcinoma (2 arms), sponsored by Fédération Francophone de Cancérologie Digestive. Primary endpoint: 10-month progression-free rate. Planned start Jul 2024; status: authorised.

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Drugs

pembrolizumabbevacizumaboxaliplatincapecitabinefluorouracil
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Conditions

colorectal cancer (CRC)colorectal adenocarcinoma

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