Trial intelligence / Profile preview

Clindamycin for the treatment of infections: influence of rifampicin and obesity on PK/PD target attainment

2024-515872-12-00Phase 4Authorised

Sponsor
UZ Leuven
Start
Jan 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of clindamycin and rifampicin in fracture-related infection (FRI), periprosthetic joint infection (PJI), hidradenitis suppurativa (HS) and 1 more (4 cohorts), sponsored by UZ Leuven. Primary endpoint: Pharmacokinetic parameters of clindamycin (and rifampicin where applicable). Planned start Jan 2025; status: authorised.

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Drugs

clindamycinrifampicin
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Conditions

fracture-related infection (FRI)periprosthetic joint infection (PJI)hidradenitis suppurativa (HS)bacterial disease

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