Trial intelligence / Profile preview

SEVILLA_A: ivonescimab versus FOLFOX in second-line advanced biliary tract cancer

2024-515875-36-00Phase 2Authorised

Sponsor
Unicancer
Start
Mar 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of ivonescimab, fluorouracil, oxaliplatin and folinic acid in biliary cancer, cholangiocarcinoma (CCA) and gallbladder cancer, sponsored by Unicancer. Primary endpoint: Progression-free survival. Planned start Mar 2025; status: authorised.

02

Drugs

ivonescimabfluorouraciloxaliplatinfolinic acid
03

Conditions

biliary cancercholangiocarcinoma (CCA)gallbladder cancer

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