Trial intelligence / Profile preview

ECLIPSE 1

2024-515919-22-00Phase 3Authorised

Sponsor
Vir Biotechnology
Start
Jun 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
11
01

Overview

Phase 3, randomised, open-label trial of tobevibart and elebsiran in hepatitis D (HDV) (2 arms), sponsored by Vir Biotechnology. Primary endpoints: Composite virologic and biochemical response and Primary safety. Planned start Jun 2025; status: authorised.

02

Drugs

tobevibartelebsiran
03

Conditions

hepatitis D (HDV)

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