Trial intelligence / Profile preview

AUSTRAL trial of radiotherapy followed by durvalumab and ceralasertib for relapsed stage III NSCLC after PACIFIC

2024-515942-18-01Phase 2Completed

Sponsor
Mario Negri Institute for Pharmacological Research
Start
Jul 2025
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
2
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Overview

Phase 2, open-label, single-arm trial of durvalumab and ceralasertib in non-small cell lung cancer (NSCLC), sponsored by Mario Negri Institute for Pharmacological Research. Primary endpoints: Safety and tolerability and Progression-free survival. Started Jul 2025; status: completed.

02

Drugs

durvalumabceralasertib
03

Conditions

non-small cell lung cancer (NSCLC)

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