Trial intelligence / Profile preview

BEACON 2 for relapsed neuroblastoma

2024-516115-24-00Phase 2Authorised

Sponsor
University of Birmingham
Start
Jul 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
15
01

Overview

Phase 2, randomised, open-label trial of Dinutuximab beta, bevacizumab, temozolomide, topotecan and irinotecan in neuroblastoma (4 arms), sponsored by University of Birmingham. Primary endpoints: Progression-free survival and Safe and tolerable combination regimen. Planned start Jul 2026; status: authorised.

02

Drugs

Dinutuximab betabevacizumabtemozolomidetopotecanirinotecan
03

Conditions

neuroblastoma

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