Trial intelligence / Profile preview

ART plus dual long-acting HIV bNAbs vs ART plus placebo in primary HIV-1 infection

2024-516150-22-00Phase 2Authorised

Sponsor
ANRS
Start
Oct 2024
Modality
Anti-infectious Disease mAbs → Neutralizing Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics, Naked Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, double-blind trial of Teropavimab and zinlirvimab in human immunodeficiency virus infection (HIV) (2 arms), sponsored by ANRS. Primary endpoint: Proportion of participants with plasma HIV-1 RNA below 400 copies/mL at 24 weeks following ATI in the confirmed absence of ART (post-treatment controllers). Planned start Oct 2024; status: authorised.

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Drugs

Teropavimabzinlirvimab
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Conditions

human immunodeficiency virus infection (HIV)

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