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PREOPANC-2: Neoadjuvant FOLFIRINOX versus gemcitabine-based chemoradiotherapy plus adjuvant gemcitabine in resectable or borderline resectable pancreatic cancer

2024-516260-29-00Phase 3Completed

Sponsor
Erasmus MC
Start
Oct 2024
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of irinotecan, folinic acid, oxaliplatin, fluorouracil and gemcitabine in pancreatic adenocarcinoma (PDAC) (2 arms), sponsored by Erasmus MC. Primary endpoint: overall survival. Started Oct 2024; status: completed.

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Drugs

irinotecanfolinic acidoxaliplatinfluorouracilgemcitabine
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Conditions

pancreatic adenocarcinoma (PDAC)

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