Trial intelligence / Profile preview

DCC-3116 plus ripretinib in advanced KIT exon 11-mutant GIST

2024-516476-15-00Phase 2Authorised

Sponsor
Deciphera Pharmaceuticals
Start
Mar 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
10
01

Overview

Phase 2, open-label, single-arm trial of inlexisertib and ripretinib in gastrointestinal stromal tumor (GIST), sponsored by Deciphera Pharmaceuticals. Primary endpoint: Objective response rate. Planned start Mar 2026; status: authorised.

02

Drugs

inlexisertibripretinib
03

Conditions

gastrointestinal stromal tumor (GIST)

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