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Changes in the tumour microenvironment after intravenous or intradermal administration of anti-CTLA-4 with anti-PD1 in melanoma

2024-516545-39-01Phase 2Authorised

Sponsor
Amsterdam University Medical Center
Start
Mar 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of ipilimumab in melanoma (2 arms), sponsored by Amsterdam University Medical Center. Primary endpoint: T cell subset frequencies and systemic activation in PBMCs. Planned start Mar 2026; status: authorised.

02

Drugs

ipilimumab
03

Conditions

melanoma

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