Trial intelligence / Profile preview

DiscovHER PAN-206 zanidatamab in previously treated HER2-expressing solid tumors

2024-516551-41-00Phase 2Authorised

Sponsor
Jazz Pharmaceuticals plc
Start
Mar 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
6
01

Overview

Phase 2, open-label trial of zanidatamab in Nonhematologic neoplasms, breast cancer, gastroesophageal junction adenocarcinoma and 2 more (3 cohorts), sponsored by Jazz Pharmaceuticals plc. Primary endpoint: Confirmed objective response rate. Planned start Mar 2026; status: authorised.

02

Drugs

zanidatamab
03

Conditions

Nonhematologic neoplasmsbreast cancergastroesophageal junction adenocarcinomacolorectal cancer (CRC)non-small cell lung cancer (NSCLC)

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