Trial intelligence / Profile preview

Carfilzomib Combinations With or Without ASCT in Newly Diagnosed Multiple Myeloma

2024-516630-35-01Phase 2Completed

Sponsor
University of Turin
Start
Jan 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of carfilzomib, lenalidomide, cyclophosphamide and dexamethasone in multiple myeloma (MM) (4 arms), sponsored by University of Turin. Primary endpoints: Rate of very good partial response or better at cycle 4 and Progression-free survival in the two maintenance arms. Started Jan 2025; status: completed.

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Drugs

carfilzomiblenalidomidecyclophosphamidedexamethasone
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Conditions

multiple myeloma (MM)

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