Trial intelligence / Profile preview

PATHOS: Risk-stratified reduced-intensity adjuvant treatment after transoral surgery for HPV-positive oropharyngeal cancer

2024-516673-68-00Phase 3Authorised

Sponsor
Cardiff University
Start
Jan 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
5
01

Overview

Phase 3, randomised trial of cisplatin and carboplatin in oropharyngeal squamous cell carcinoma (2 arms), sponsored by Cardiff University. Primary endpoints: Overall survival and Swallowing function (MD Anderson Dysphagia Inventory score). Planned start Jan 2025; status: authorised.

02

Drugs

cisplatincarboplatin
03

Conditions

oropharyngeal squamous cell carcinoma

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