Trial intelligence / Profile preview

OAsIs: Obinutuzumab + Venetoclax + Ibrutinib in Mantle Cell Lymphoma

2024-516750-21-00Phase 2Completed

Sponsor
CHU de Nantes
Start
Oct 2015
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
2
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Overview

Phase 2, open-label trial of obinutuzumab, venetoclax and ibrutinib in mantle cell lymphoma (MCL) (3 arms), sponsored by CHU de Nantes. Primary endpoints: Unacceptable toxicity of GA101 + Ibrutinib (Step A), Dose-limiting toxicities of GA101 + Ibrutinib + GDC-0199 (Step B) and 1 more. Started Oct 2015; status: completed.

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Drugs

obinutuzumabvenetoclaxibrutinib
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Conditions

mantle cell lymphoma (MCL)

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