Trial intelligence / Profile preview

RADIAN

2024-516779-33-00Phase 2Authorised

Sponsor
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello
Start
Aug 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of niraparib and dostarlimab in head and neck squamous cell carcinoma (HNSCC), oropharyngeal squamous cell carcinoma (OPSCC), laryngeal squamous cell carcinoma (LSCC) and 2 more (2 cohorts), sponsored by Grupo Español de Tratamiento de Tumores de Cabeza y Cuello. Primary endpoint: 1-year disease-free survival. Planned start Aug 2024; status: authorised.

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Drugs

niraparibdostarlimab
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Conditions

head and neck squamous cell carcinoma (HNSCC)oropharyngeal squamous cell carcinoma (OPSCC)laryngeal squamous cell carcinoma (LSCC)squamous cell carcinoma of the hypopharynxOral Mucosal Carcinoma

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