Trial intelligence / Profile preview

First-in-human ADCE-D01 in metastatic/unresectable soft tissue sarcoma (ADCElerate 1)

2024-516900-41-00Phase 2Authorised

Sponsor
Adcendo
Start
Apr 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Countries
5
01

Overview

Phase 2, open-label, single-arm trial of ADCE-D01 in soft tissue sarcoma (STS), sponsored by Adcendo. Primary endpoints: Incidence of dose-limiting toxicities (DLTs), Treatment-emergent adverse events (TEAEs) and laboratory changes (Phase 1a/1b) and 5 more. Planned start Apr 2025; status: authorised.

02

Drugs

ADCE-D01
03

Conditions

soft tissue sarcoma (STS)

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