Trial intelligence / Profile preview

Belzutifan + zanzalintinib versus belzutifan + placebo in previously treated advanced renal cell carcinoma

2024-516993-31-00Phase 3Authorised

Sponsor
Merck & Co.
Start
May 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
19
01

Overview

Phase 3, randomised, double-blind trial in renal cell carcinoma (RCC) comparing Belzutifan + zanzalintinib with Belzutifan + placebo (2 arms). Primary endpoints: Progression Free Survival and Overall Survival. Planned start May 2026; status: authorised.

02

Drugs

belzutifanzanzalintinib
03

Conditions

renal cell carcinoma (RCC)

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