Trial intelligence / Profile preview

IPCOM: Influence of Proton Pump Inhibitor Co-medication on Mycophenolate Mofetil Absorption

2024-517043-32-00Phase 4Completed

Sponsor
Leiden University Medical Center
Start
Feb 2025
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of mycophenolate mofetil and pantoprazole in immunocompromise, sponsored by Leiden University Medical Center. Primary endpoints: Maximum plasma concentration (Cmax) of mycophenolic acid (MPA) and Area under the concentration-time curve AUC(0–12) of mycophenolic acid (MPA). Started Feb 2025; status: completed.

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Drugs

mycophenolate mofetilpantoprazole
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Conditions

immunocompromise

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