Trial intelligence / Profile preview

Sonrotoclax combinations versus venetoclax + rituximab in relapsed/refractory CLL/SLL

2024-517131-52-00Phase 3Authorised

Sponsor
BeOne Medicines
Start
Nov 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
21
01

Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing BGB-11417 + obinutuzumab, BGB-11417 + rituximab and venetoclax + rituximab (3 arms). Primary endpoint: Progression-free survival. Planned start Nov 2025; status: authorised.

02

Drugs

sonrotoclaxobinutuzumabrituximabvenetoclax
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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Available in the Gosset platform where reported.

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