Trial intelligence / Profile preview

Imlifidase for acute AQP4-IgG-positive neuromyelitis optica spectrum disorder

2024-517176-38-00Phase 2Completed

Sponsor
Erasmus MC
Start
Aug 2025
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of efgartigimod alfa in Neuromyelitis Optica Spectrum Disorder (NMOSD), sponsored by Erasmus MC. Primary endpoint: Depletion of circulating pathogenic anti-AQP4 IgG. Started Aug 2025; status: completed.

02

Drugs

efgartigimod alfa
03

Conditions

Neuromyelitis Optica Spectrum Disorder (NMOSD)

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