Trial intelligence / Profile preview

GLORA-4: lisaftoclax plus azacitidine versus placebo plus azacitidine in newly diagnosed higher-risk myelodysplastic syndrome

2024-517247-31-00Phase 3Authorised

Sponsor
Ascentage Pharma
Start
Jul 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
19
01

Overview

Phase 3, randomised, double-blind trial in myelodysplastic syndrome (MDS) comparing Lisaftoclax + azacitidine with Placebo + azacitidine (2 arms). Planned start Jul 2025; status: authorised.

02

Drugs

lisaftoclaxazacitidine
03

Conditions

myelodysplastic syndrome (MDS)

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