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PREVENT trial: preventive HIPEC plus perioperative FLOT versus FLOT alone in resectable diffuse gastric or gastroesophageal junction adenocarcinoma

2024-517300-10-01Phase 3Authorised

Sponsor
Krankenhaus Nordwest
Start
Dec 2020
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of fluorouracil, folinic acid, oxaliplatin, docetaxel and cisplatin in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by Krankenhaus Nordwest. Primary endpoint: Progression-free survival / disease-free survival. Planned start Dec 2020; status: authorised.

02

Drugs

fluorouracilfolinic acidoxaliplatindocetaxelcisplatin
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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