Trial intelligence / Profile preview

KANDLELIT-013 adjuvant MK-1084 plus MK-3475A versus placebo plus MK-3475A in resected KRAS G12C-mutant non-small cell lung cancer

2024-517337-41-00Phase 3Authorised

Sponsor
Merck & Co.
Start
May 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
24
01

Overview

Phase 3, randomised, double-blind trial of calderasib and pembrolizumab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Merck & Co. Primary endpoint: Disease-Free Survival. Planned start May 2026; status: authorised.

02

Drugs

calderasibpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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