Trial intelligence / Profile preview

STROBE: HRD Status and Benefit from Olaparib + Bevacizumab in Advanced Ovarian Cancer

2024-517363-24-00Phase 2Authorised

Sponsor
Vall d'Hebron Institute of Oncology
Start
Nov 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of olaparib and bevacizumab in High-Grade Serous Ovarian Cancer (HGSOC), Endometrioid Cystadenocarcinoma, fallopian tube cancer (PFTC) and 1 more, sponsored by Vall d'Hebron Institute of Oncology. Primary endpoint: Percentage of HR status agreement between VHIO-CARD-300 test and SOPHiA DDM Dx HRD Solution. Planned start Nov 2024; status: authorised.

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Drugs

olaparibbevacizumab
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Conditions

High-Grade Serous Ovarian Cancer (HGSOC)Endometrioid Cystadenocarcinomafallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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