Trial intelligence / Profile preview

ICONIC

2024-517378-22-00Phase 2Authorised

Sponsor
Fondazione Centro Nazionale di Adroterapia Oncologica
Start
Nov 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of pembrolizumab, atezolizumab, nivolumab and cemiplimab in melanoma, transitional cell carcinoma (TCC), non-small cell lung cancer (NSCLC) and 1 more, sponsored by Fondazione Centro Nazionale di Adroterapia Oncologica. Primary endpoints: Objective response rate (ORR) according to RECIST and Toxicity according to CTCAE v5.0. Planned start Nov 2024; status: authorised.

02

Drugs

pembrolizumabatezolizumabnivolumabcemiplimab
03

Conditions

melanomatransitional cell carcinoma (TCC)non-small cell lung cancer (NSCLC)head and neck squamous cell carcinoma (HNSCC)

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