Trial intelligence / Profile preview

BOLD-100 plus FOLFOX with or without bevacizumab in advanced gastrointestinal solid tumors

2024-517500-11-00Phase 2Authorised

Sponsor
Bold Therapeutics
Start
Jul 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Light/Condition-Responsive Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
7
01

Overview

Phase 2, open-label trial of BOLD-100 in colorectal cancer (CRC), gastric cancer (GC), pancreatic cancer (PC) and 4 more (2 arms), sponsored by Bold Therapeutics. Primary endpoints: Incidence and severity of adverse events, Incidence of serious adverse events and suspected unexpected serious adverse reactions and 5 more. Planned start Jul 2025; status: authorised.

02

Drugs

BOLD-100
03

Conditions

colorectal cancer (CRC)gastric cancer (GC)pancreatic cancer (PC)cholangiocarcinoma (CCA)gallbladder cancer

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