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Metformin versus Tolvaptan in adults with Autosomal Dominant Polycystic Kidney Disease

2024-517864-49-01Phase 3Authorised

Sponsor
University of Bari Aldo Moro
Start
Jan 2025
Modality
Small Molecules
Countries
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Overview

Phase 3, randomised trial in autosomal dominant polycystic kidney disease (ADPKD) comparing Metformin with Tolvaptan (Jinarc) (2 arms). Primary endpoint: Annualized slope of eGFR (CKD-EPI). Planned start Jan 2025; status: authorised.

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Drugs

metformintolvaptan
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Conditions

autosomal dominant polycystic kidney disease (ADPKD)

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