Trial intelligence / Profile preview

MK-6070 and ifinatamab deruxtecan in relapsed/refractory extensive-stage small cell lung cancer

2024-517926-25-00Phase 2Authorised

Sponsor
Merck & Co.
Start
Mar 2025
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
12
01

Overview

Phase 2, open-label trial of gocatamig, ifinatamab deruxtecan and durvalumab in small cell lung cancer (SCLC) (5 arms), sponsored by Merck & Co. Primary endpoints: Number of participants who experience an adverse event, Number of participants who experience one or more dose-limiting toxicities and 2 more. Planned start Mar 2025; status: authorised.

02

Drugs

gocatamigifinatamab deruxtecandurvalumab
03

Conditions

small cell lung cancer (SCLC)

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