Trial intelligence / Profile preview

PACE-Lung: Added chemotherapy for persistent plasma EGFR ctDNA after starting first-line osimertinib

2024-517965-18-00Phase 2Completed

Sponsor
Goethe University Frankfurt
Start
Nov 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of osimertinib, pemetrexed, cisplatin and carboplatin in non-small cell lung cancer (NSCLC), sponsored by Goethe University Frankfurt. Primary endpoint: Progression-free survival 1. Started Nov 2021; status: completed.

02

Drugs

osimertinibpemetrexedcisplatincarboplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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