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Intraoperative methadone for prevention of postoperative pain in orthopedic arthroplasty
2024-518059-50-00Phase 3Authorised
- Sponsor
- CHU Brugmann
- Start
- Mar 2023
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, double-blind trial in postoperative pain comparing Methadone hydrochloride arm with Sufentanil arm (2 arms). Primary endpoints: Total postoperative morphine consumption, Postoperative pain at rest and 4 more. Planned start Mar 2023; status: authorised.
02
Drugs
methadonesufentanil
03
Conditions
postoperative pain
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