Trial intelligence / Profile preview

Preoperative FOLFOX versus postoperative risk-adapted chemotherapy for locally advanced rectal cancer with low local failure risk

2024-518077-34-00Phase 3Authorised

Sponsor
Heidelberg University
Start
Sep 2020
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of oxaliplatin, capecitabine, fluorouracil and folinic acid in rectal adenocarcinoma (2 arms), sponsored by Heidelberg University. Primary endpoint: Disease-free survival. Planned start Sep 2020; status: authorised.

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Drugs

oxaliplatincapecitabinefluorouracilfolinic acid
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Conditions

rectal adenocarcinoma

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