Trial intelligence / Profile preview

Intensive versus standard adjuvant chemotherapy in ctDNA-positive localized colon cancer

2024-518131-11-02Phase 2Authorised

Sponsor
Instituto de Investigación Sanitaria Hospital Clínico San Carlos
Start
Jan 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of capecitabine, oxaliplatin, fluorouracil, irinotecan and folinic acid in colon cancer (2 arms), sponsored by Instituto de Investigación Sanitaria Hospital Clínico San Carlos. Primary endpoints: Phase IIa ctDNA clearance rate and Phase IIb ctDNA clearance comparison. Planned start Jan 2025; status: authorised.

02

Drugs

capecitabineoxaliplatinfluorouracilirinotecanfolinic acid
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Conditions

colon cancer

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