Trial intelligence / Profile preview

Randomized phase II study of osimertinib-first versus dacomitinib-first EGFR-TKI sequencing in EGFR-mutated advanced NSCLC

2024-518223-29-00Phase 2Authorised

Sponsor
Fondazione Ricerca Traslazionale
Start
Mar 2020
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
2
01

Overview

Phase 2, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Osimertinib first with Dacomitinib first (2 arms). Primary endpoint: Overall survival. Planned start Mar 2020; status: authorised.

02

Drugs

osimertinibdacomitinib
03

Conditions

non-small cell lung cancer (NSCLC)

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