Trial intelligence / Profile preview

Personalized AI-assisted treatment in neovascular AMD

2024-518482-99-01Phase 4Authorised

Sponsor
Medical University of Vienna
Start
Jan 2025
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, randomised trial in exudative macular degeneration comparing AI-guided aflibercept (Eylea), AI-guided ranibizumab (Lucentis) and AI-guided brolucizumab (Beovu) (3 arms). Primary endpoint: Number of anti-VEGF injections. Planned start Jan 2025; status: authorised.

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Drugs

afliberceptranibizumabbrolucizumab
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Conditions

exudative macular degeneration

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