Trial intelligence / Profile preview

Phase 2/3 Study of Telisotuzumab Adizutecan + Osimertinib as First-Line Therapy in EGFR-Mutated Non-Squamous NSCLC

2024-518586-10-00Phase 3Authorised

Sponsor
AbbVie Inc.
Start
Aug 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Countries
13
01

Overview

Phase 3, randomised trial of telisotuzumab adizutecan in Non-small cell lung cancer (NS-NSCLC) (2 arms), sponsored by AbbVie Inc. Primary endpoints: Phase 2: Objective response (OR) and Phase 3: Progression-free survival (PFS). Planned start Aug 2025; status: authorised.

02

Drugs

telisotuzumab adizutecan
03

Conditions

Non-small cell lung cancer (NS-NSCLC)

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