Trial intelligence / Profile preview

Ivonescimab versus Keytruda in first-line metastatic NSCLC with high PD-L1 expression

2024-518629-14-00Phase 3Authorised

Sponsor
Summit Therapeutics
Start
Jun 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
18
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Ivonescimab with Keytruda (2 arms). Primary endpoints: Overall survival and Progression-free survival. Planned start Jun 2025; status: authorised.

02

Drugs

ivonescimabpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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