Trial intelligence / Profile preview

CHARCOT study

2024-518637-28-00Phase 3Completed

Sponsor
Amsterdam University Medical Center
Start
Nov 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in Charcot neuroarthropathy (CN), diabetes mellitus type 1 (T1D) and type 2 diabetes mellitus (T2DM) comparing Denosumab with Saline placebo (2 arms). Primary endpoint: Time to cession of total contact cast with fracture healing. Started Nov 2024; status: completed.

02

Drugs

denosumab
03

Conditions

Charcot neuroarthropathy (CN)diabetes mellitus type 1 (T1D)type 2 diabetes mellitus (T2DM)

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