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SIGNAL – Urinary proteomics-guided early intervention in type 2 diabetes

2024-518682-95-00Phase 4Authorised

Sponsor
Steno Diabetes Center Copenhagen
Start
Feb 2025
Modality
Recombinant Proteins and Enzymes, Peptides, Small Molecules
Countries
2
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Overview

Phase 4, single-arm trial of dapagliflozin, semaglutide and finerenone in type 2 diabetes mellitus (T2DM), diabetic glomerulosclerosis and cardiac morbidity, sponsored by Steno Diabetes Center Copenhagen. Primary endpoints: Feasibility of obtaining urine proteomic results within 2 weeks and Feasibility of interpreting urine proteomic results for treatment evaluation. Planned start Feb 2025; status: authorised.

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Drugs

dapagliflozinsemaglutidefinerenone
03

Conditions

type 2 diabetes mellitus (T2DM)diabetic glomerulosclerosiscardiac morbidity

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