Trial intelligence / Profile preview

Phase 2 study of RLY-2608 in PIK3CA-related overgrowth spectrum and PIK3CA-driven malformations

2024-518895-30-00Phase 2Authorised

Sponsor
Relay Therapeutics
Start
Nov 2025
Modality
Small Molecules
Countries
11
01

Overview

Phase 2, randomised, open-label trial of zovegalisib in PIK3CA-related overgrowth spectrum (PROS) and vascular malformation (3 arms), sponsored by Relay Therapeutics. Primary endpoints: Recommended phase 2 dose, Overall safety profile and 1 more. Planned start Nov 2025; status: authorised.

02

Drugs

zovegalisib
03

Conditions

PIK3CA-related overgrowth spectrum (PROS)vascular malformation

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