Trial intelligence / Profile preview

PANACHE02 risk-adapted adjuvant chemotherapy after neoadjuvant mFOLFIRINOX and surgery for pancreatic adenocarcinoma

2024-519048-33-00Phase 3Authorised

Sponsor
Rouen University Hospital
Start
Nov 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of fluorouracil, irinotecan, folinic acid, oxaliplatin, gemcitabine and 1 more in pancreatic adenocarcinoma (PDAC) (2 arms), sponsored by Rouen University Hospital. Primary endpoints: Disease-free survival and Overall survival. Planned start Nov 2025; status: authorised.

02

Drugs

fluorouracilirinotecanfolinic acidoxaliplatingemcitabine
03

Conditions

pancreatic adenocarcinoma (PDAC)

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