Trial intelligence / Profile preview

Iceland Screens Treats or Prevents Multiple Myeloma (iStopMM) Phase 2 Trial of Smoldering and Active MM

2024-519353-11-00Phase 2Authorised

Sponsor
Landspitali
Start
Dec 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 2, open-label trial of carfilzomib, lenalidomide and dexamethasone in multiple myeloma (MM) and smoldering multiple myeloma (SMM), sponsored by Landspitali. Primary endpoint: Proportion of MRD-negative participants at 3 years. Planned start Dec 2024; status: authorised.

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Drugs

carfilzomiblenalidomidedexamethasone
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Conditions

multiple myeloma (MM)smoldering multiple myeloma (SMM)

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