Trial intelligence / Profile preview

DESTINY-Endometrial02 adjuvant T-DXd versus standard chemotherapy in HER2-expressing endometrial cancer

2024-519444-33-00Phase 3Authorised

Sponsor
Daiichi Sankyo Co., Ltd.
Start
Mar 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
19
01

Overview

Phase 3, randomised, open-label trial in endometrial cancer (EC) comparing Trastuzumab deruxtecan arm with Standard-of-care arm (2 arms). Primary endpoint: Disease-free survival by blinded independent central review. Planned start Mar 2026; status: authorised.

02

Drugs

trastuzumab deruxtecan
03

Conditions

endometrial cancer (EC)

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