Trial intelligence / Profile preview

CHIMERA trial of first-line trastuzumab deruxtecan + capecitabine + bevacizumab in HER2-positive metastatic colorectal cancer

2024-519479-24-00Phase 2Authorised

Sponsor
G.O.N.O. - Gruppo Oncologico del Nord Ovest
Start
Oct 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
4
01

Overview

Phase 2, open-label trial of trastuzumab deruxtecan, capecitabine and bevacizumab in colorectal cancer (CRC) and metastatic colorectal adenocarcinoma (mCRC), sponsored by G.O.N.O. - Gruppo Oncologico del Nord Ovest. Planned start Oct 2025; status: authorised.

02

Drugs

trastuzumab deruxtecancapecitabinebevacizumab
03

Conditions

colorectal cancer (CRC)metastatic colorectal adenocarcinoma (mCRC)

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