Trial intelligence / Profile preview

CARAMEL phase I/II trial of CNTY-101 with aldesleukin for B-cell depletion in autoimmune disease

2024-519532-16-00Phase 2Authorised

Sponsor
Universitätsklinikum Erlangen
Start
May 2025
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes, CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies
Countries
1
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Overview

Phase 2, open-label, single-arm trial of CNTY-101 and aldesleukin in systemic lupus erythematosus (SLE), Autoimmune Myopathies and systemic sclerosis (SSc), sponsored by Universitätsklinikum Erlangen. Primary endpoint: Dose-limiting safety composite. Planned start May 2025; status: authorised.

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Drugs

CNTY-101aldesleukin
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Conditions

systemic lupus erythematosus (SLE)Autoimmune Myopathiessystemic sclerosis (SSc)

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