Trial intelligence / Profile preview

SHASTA-10 long-term extension study of plozasiran in adults with hypertriglyceridemia

2024-519712-13-00Phase 3Authorised

Sponsor
Arrowhead Pharmaceuticals
Start
Dec 2025
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
22
01

Overview

Phase 3, open-label, single-arm trial of plozasiran in hypertriglyceridemia, sponsored by Arrowhead Pharmaceuticals. Primary endpoint: Incidence of treatment-emergent adverse events. Planned start Dec 2025; status: authorised.

02

Drugs

plozasiran
03

Conditions

hypertriglyceridemia

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