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COMBINE: Elacestrant plus exemestane in pretreated HR+/HER2- metastatic breast cancer with FES-avid disease

2024-519792-25-00Phase 2Authorised

Sponsor
European Institute of Oncology
Start
Oct 2025
Modality
Small Molecules, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of elacestrant and exemestane in breast cancer, sponsored by European Institute of Oncology. Primary endpoint: 6-month progression-free survival rate per RECIST v1.1. Planned start Oct 2025; status: authorised.

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Drugs

elacestrantexemestane
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Conditions

breast cancer

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