Trial intelligence / Profile preview

UPROOT study of obinutuzumab in primary Sjögren's syndrome

2024-519884-16-00Phase 2Authorised

Sponsor
Radboud University Medical Center
Start
Mar 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of obinutuzumab in primary Sjögren's syndrome, sponsored by Radboud University Medical Center. Primary endpoint: Autoreactive B-cell depletion at 3 months. Planned start Mar 2026; status: authorised.

02

Drugs

obinutuzumab
03

Conditions

primary Sjögren's syndrome

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